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4 October 2022 by 
Cite as: De Vuyst, Geert (4 October 2022) The anti-SARS-CoV-2 properties of essential oils, aromatic extracts and F&F raw materials. Geert De Vuyst.

The anti-SARS-CoV-2 properties of essential oils, aromatic extracts and F&F raw materials

Photo Xiaolong Wong @

Photo Xiaolong Wong @

In their August 2022 study, Strub and colleagues investigate the anti‑SARS‑CoV‑2 activity of 538 essential oils, aromatic extracts and F&F raw materials (natural flavors and fragrances).

Substances with a high monoterpene and monoterpenoid content have no or the lowest activity against the viruses that cause SARS (Severe Acute Respiratory Syndrome). Petitgrain mandarin (Citrus reticulata, steam distillation, leaf) steals the show, possibly due to its high concentration of dimethyl anthranilate (DMA).

This is an “Expert” article. This article is not intended to substitute professional medical advice, diagnosis or treatment. Read the Terms of Use. If you start with essential oils, read the Safety Precautions

New research by Strub and colleagues in Scientific Reports

Translation is in progress. This article was originally published in Dutch. Read the article at the Aroma Blog.

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Information on extract composition refers to supplier analysis sheets: Ladrôme (date of the analysis); Pranarôm International (lot number, e.g. OF20610).


Astani, A., Reichling, J., & Schnitzler, P. (2010). Comparative study on the antiviral activity of selected monoterpenes derived from essential oilsPhytotherapy Research24(5), 673–679.

Baharom, N., Sulaiman, W. S. W., Rashid, Z. Z., Ken, W. K., Ali, U. K., Othman, S. N., Samat, M. N., Kori, N., Periyasamy, P., Zakaria, N. A., Sugurmar, A. N. K., Kazmin, N. E. M., Khee, C. X., Saniman, S. M.,, & Isahak, I. Early viral clearance among covid‑19 patients when gargling with povidone‑iodine and essential oils – a clinical trialPreprint

Hu, Q., Xiong, Y., Zhu, G. H., Zhang, Y. N., Zhang, Y. W., Huang, P.,, & Ge, G. B. (2022). The SARS‐CoV‐2 main protease (M pro ): Structure, function, and emerging therapies for COVID‐19MedComm3(3).

Narayanan, A., Narwal, M., Majowicz, S. A., Varricchio, C., Toner, S. A., Ballatore, C., Brancale, A., Murakami, K. S.,, & Jose, J. (2022). Identification of SARS‑CoV‑2 inhibitors targeting Mpro and PLpro using in‑cell‑protease assayCommunications Biology5(1).

Strub, D. J., Talma, M., Strub, M., Rut, W., Zmudzinski, M., Brud, W., Neyts, J., Vangeel, L., Zhang, L., Sun, X., Lv, Z., Nayak, D., Olsen, S. K., Hilgenfeld, R., Jochmans, D., & Drąg, M. (2022). Evaluation of the anti‑SARS‑CoV‑2 properties of essential oils and aromatic extractsScientific Reports12(1).


Tisserand, R. & Young, R. (2014) Essential Oil Safety (2 ed.) Elsevier – Churchill Livingstone


NIH DailyMed database: LISTERINE ORIGINAL ANTISEPTIC – Johnson & Johnson Consumer Inc.

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